Search by FRAC Mode of Action Groups for Recommendations

The FRAC Mode of Action (MoA) classification provides growers, advisors, extension staff, consultants and crop protection professionals with a guide to the selection of fungicides for use in an effective and sustainable fungicide resistance management strategy.
 

Due to the structure of FRAC Working Groups, please find Recommendations for Resistance Management in Bananas by following this link:
Link to Recommendations for Resistance Management in Banana.
 

Get forwarded to FRAC Recommendations for Fungicide Resistance by clicking on the links in the table below based on the Mode of Action and the FRAC Mode of Action Code number as printed on label of Plant Protection Products as well as several commonly used synonyms. Additionally, a sorting according to the FRAC MoA Code numbers is available in the second table underneath.

Labelling

FRAC acknowledged Mode of Action (MoA) and

links to Recommendations for FRAC MoA Groups

Synonyms, examples

 
  Inhibitor of ß-tubulin assembly in mitosis:

GROUP

1

MBC fungicides

B1, Methyl Benzimidazole Carbamates, Benzimidazoles, BA, BCM

GROUP

10

NPC fungicides

B2, N-Phenyl Carbamates

 
  Inhibitor of osmotic signal transduction

GROUP

2

Dicarboximide fungicides

E3, DI

 
  Sterol biosynthesis inhibitor (SBI) fungicides:

GROUP

3

SBI Class I: DMI-fungicides

G1, DeMethylation Inhibitors, Azoles, Triazoles, erg11, cyp51

GROUP

5

SBI Class II: Amines

G2, Morpholines, erg2-, erg24-gene

GROUP

17

SBI Class III: KRI fungicide

G3, KetoReductase Inhibitors, erg27-gene

GROUP

18

SBI Class IV

G4, Squalene-epoxidase in sterol biosynthesis

 
  Inhibitor of RNA polymerase I

GROUP

4

PA fungicides

A1, PhenylAmides, Acylalanines,

 
  Inhibitor of respiration in complex II at SDH

GROUP

7

SDHI fungicides

C2, Succinate dehydrogenase inhibitors, Carboxamides, sdh-gene

 
  Inhibition of methionine biosynthesis
(proposed)

GROUP

9

AP fungicides

D1, Anilino-Pyrimidine

 
  Inhibitor of respiration in complex III at Qo-site

GROUP

11

QoI-fungicides

C3, Quinone outside Inhibitors, Strobilurines, cyt-b-gene

 
  Inhibitors of signal transduction

GROUP

13

AZN fungicides

E1, Azanaphthalenes

 
  Cellulose synthase inhibitors

GROUP

40

CAA fungicides

H5, Carboxylic Acid Amides

 
  Lipid homeostasis and transfer/storage inhibitor

GROUP

49

OSBPI fungicides

F9, OxySterol Binding Protein Inhibitors


 
 
Get forwarded to FRAC Recommendations for Fungicide Resistance by clicking on the links in the table below based on the FRAC Mode of Action Code number as printed on label of Plant Protection Products as well as several commonly used synonyms.

Labelling

Links to Recommendations for FRAC Mode of Action Groups

Synonyms, examples

         

GROUP

1

MBC fungicides

B1, Methyl Benzimidazole Carbamates, Benzimidazoles, BA, BCM  
         

GROUP

2

Dicarboximide fungicides

E3, DI
         

GROUP

3

SBI Class I: DMI-fungicides

G1, DeMethylation Inhibitors, Azoles, Triazoles, erg11, cyp51
         

GROUP

4

PA fungicides

A1, PhenylAmides, Acylalanines,
         

GROUP

5

SBI Class II: Amines

G2, Morpholines, erg2-, erg24-gene
       

GROUP

7

SDHI fungicides
C2, Succinate dehydrogenase inhibitors, Carboxamides, sdh-gene
       

GROUP

9

AP fungicides D1, Anilino-Pyrimidine
       

GROUP

10

NPC fungicides B2, N-Phenyl Carbamates
   

GROUP

11

 QoI-fungicides  C3, Quinone outside Inhibitors, Strobilurines, cyt-b-gene
   

GROUP

13

AZN fungicides  E1, Azanaphthalenes
   

GROUP

17

SBI Class III: KRI fungicide

G3, KetoReductase Inhibitors, erg27-gene
   

GROUP

18

SBI Class IV

G4, Squalene-epoxidase in sterol biosynthesis
   

GROUP

40

CAA fungicides

H5, Carboxylic Acid Amides
   

GROUP

49

OSBPI fungicides

F9, OxySterol Binding Protein Inhibitors


 
Resistance Management Recommendations for Modes of Action not covered by FRAC Working Groups

This section contains FRAC approved company resistance management recommendations for fungicide MoAs not covered by an active working group. Please refer to the FRAC Code List for important comments on resistance management.

  • Which Fungicides belong to the same FRAC MoA Group. Fungicides of the same FRAC MoA Group are expected to demonstrate a degree of cross resistance once field resistance arises. They are thus not seen as suitable mixing or alternating partners for resistance management purposes.
  • The intrinsic risk of the MoA group, to be used for resistance risk analysis of fungicides (‘low’, ‘medium’ or ‘high’); which defines the need for resistance management.
  • Comments on known (molecular) resistance mechanisms and resistant pathogens (full list, please look here)

 

For some Mode of Action Groups the manufacturers provided FRAC with recommendations:

  
FRAC statement on multisite fungicides:

Contact

Dr. Dietrich Hermann
Chair

Syngenta Crop Protection AG
Research and Development
WRO B4-1-129
CH 4002 Basel, Switzerland

Tel: +41 61 32 30983
dietrich.hermann@syngenta.com

Dr. Juergen Derpmann
FRAC Communication and Website Officer

Bayer AG,
Crop Science Division


juergen.derpmann@bayer.com

Duncan McKenzie
Scientific Support Officer

Consultant
Switzerland

duncanmckenzie50@gmail.com