As shown in the table, the group name Carboxylic Acid Amides (CAA) has been chosen. This name best represents compounds from the three different chemical groups.
The mode of action of CAA compounds is directly linked to the inhibition of cellulose synthesis in the Oomycete plant pathogen (Blum et al. 2010).
Uptake studies with 14C labelled Mandipropamid (MPD) showed that this Oomycete control agent acts on the cell wall and does not enter the cell. Furthermore, 14C glucose incorporation into cellulose was perturbed in the presence of MPD. Gene sequence analysis of cellulose synthase genes in laboratory mutants, insensitive to MPD, revealed two point mutations in the PiCesA3 gene. This gene is known to be involved in cellulose synthesis. Both mutations in the PiCesA3 gene result in a change to the same amino acid (Glycine-1105) in the protein.