The anilinopyrimidines (APs) are a group of fungicides highly active against a broad range of fungi. Commercialised APs include cyprodinil, pyrimethanil and mepanipyrim. The mode of action includes inhibition of methionine biosynthesis and secretion of hydrolytic enzymes. APs are cross-resistant, but show no cross-resistance with other fungicide groups.

The FRAC-AP group discusses the sensitivity situation and use guidelines for control of Botrytis and Venturia.

The use of APs for control of Black Sigatoka is included in FRAC banana working group.

Update following the latest FRAC-AP meeting held on November 30th, 2007:
The current sensitivity status of Botrytis in vines and strawberries as well as the status of Venturia in apple was discussed.

Botrytis:

Vineyards:

Disease pressure in commercial vineyards in Europe was moderate whereas it was low in Australia and New Zealand in 2007.

Sensitivity monitoring was carried out in France , Spain , Portugal , Germany , New Zealand and Australia in commercial vineyards. Available data to date (2007), from France , Germany , New Zealand and Australia show that the frequency of resistant isolates continues to remain low. No resistant isolates were detected in Spain and Portugal  

Strawberries:

Disease pressure in commercial sites in Europe during 2007 was variable, ranging from low to high depending on location.

Sensitivity monitoring was carried out in Germany , UK and Spain in commercial sites. Data from 2007 show that the frequency of resistant isolates is low to moderate. 

Products, applied according to the FRAC-AP guidelines for both crops, maintained very good performance in the field after many years of commercial use.

Evidence from field and laboratory trials has shown that there is a medium resistance risk of Botrytis to APs. The fact that resistant isolates can be found in commercial sites, albeit at low levels, reinforces the importance of strict adherence to the FRAC-AP guidelines to control Botrytis.

  
Venturia:
Low to moderate disease pressure was present throughout the season in commercial orchards in Europe in 2007.

Sensitivity monitoring in commercial orchards was carried out in Europe . Resistant isolates were found at low to moderate frequency. Samples showing resistance were detected in Germany , France , Italy , Greece , Portugal , UK , and Switzerland . No resistance was detected in Russia , Spain and Serbia Montenegro.

Evidence from previous field and laboratory trials has shown that there is a medium resistance risk of Venturia to APs. The fact that resistant isolates can be found in commercial orchard reinforces the importance of strict adherence to the FRAC-AP guidelines to control Venturia.

In 2007, AP-containing spray programmes continued to show good performance in commercial orchards.