Introduction

Benzimidazoles are low use-rate, broad-spectrum fungicides that have been used commercially for the control of plant diseases since the late 1960’s. At the time of their introduction, they represented a ground-breaking class of fungicides with unique properties including systemic and curative activity that allowed extended spray intervals. World-wide, benzimidazole fungicides are registered in many countries on more than 70 crops including cereals, grapes, fruits and vegetables. Benzimidazoles currently commercially available include the active ingredients benomyl, carbendazim (MBC), thiabendazole, thiophanate, thiophanate-methyl and fuberidazole.

Code Target site of action Group name Chemical group Common name Comments
1 B-tubulin assembly in mitosis MBC-fungicides Methyl Benzimidazole Carbamates benzimid-azoles benomyl
carbendazim
fuberidazole
thiabendazole
Resistance common in many fungal species. Several target site mutations, mostly E198A/G/K, F200Y in B-tubulin gene

Positive cross resistance between thge group members. Negative cross resistance to N- Phenylcarbamates.

High risk. See FRAC Benzimidazole Guidelines for resistance management.
thiophanates thiophanate thiophanate-methyl

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Jean-Luc Genet
Chair

DuPont de Nemours (France) S.A.S.
Crop Protection
24, rue du moulin F-6870 Nambsheim, France

Tel. +33 38 98 32 712
Fax. +33 38 98 32 727
Jean-Luc.Genet@dupont.com